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Sunday brings the initial Wear-Tyne derby since 2024, but who will emerge victorious – Sunderland or the Magpies?
"During the bulk of last season, you couldn't have imagined the Wearside club earning promotion and holding their own with Eddie Howe's Newcastle, let alone being above them in the table," remarked football expert Chris Sutton.
"It is very different now, and the way Sunderland play makes me think they've got a real chance."
He is offering scoreline guesses for all 380 Premier League games this campaign, against AI, readers and a variety of guests.
For this weekend's fixtures, he takes on England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the eLions – the Football Association's official esports team – at the gaming title digital Euros finals tournament, which is being held at Twickenham Stadium on Saturday.
Viewers can catch Uefa's YouTube, Instagram Live and TikTok channels, as well as the official Twitch channel and YouTube and the national team's Twitch.
Are you in alignment with their predictions? Share your own predictions below.
The fan-favourite scoreline chosen for each game is displayed on the tables at the foot of this page.
A correct result (picking a win, draw or defeat) is worth 10 points. An accurate scoreline earns 40 points.
Ray, who represents his club side and Manchester City as well as England, is making his debut at the eEuros finals after getting through the preliminary stage.
Eight players will fly the flag at the finals in a single-elimination, playing for a $100,000 prize pool and a prestigious spot in the FC Pro World Championship Play-Ins, with the Danish representative Anders Vejrgang looking to retain the title he won last year.
"I am feeling really good for it," Ray said. "I've got a really good coach alongside me and practice has been going well.
"It is invariably an honour to play for your country. Obviously when you are younger, you dream about doing it as an actual footballer, but when you pursue a career in this job and there is an chance to represent England, donning the national jersey is something special.
"I overcame Vejrgang 9-4 in qualifying to get here. I've played against him recently just in practice, and in other tournaments before - but I'd always lost to him in a tournament before.
"For me he is the number one in the world so getting a win over him in a tournament like this just delivers a crazy boost of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The Blues were outstanding against the Gunners at the end of November, when they got a draw after being reduced to 10 men, and many thought this is it, they could possibly be title contenders.
However, since that game, however, they were overpowered by Leeds, looked uninspired against Bournemouth and this week got turned over by Atalanta in the Champions League.
So head coach Enzo Maresca really needs a win here to return to winning ways, but it is a tough ask because the Merseyside club are such a dangerous team.
Their key midfielders are playing at the top of their game and they have got a bit of momentum at the moment.
Current evidence suggests you would likely back the visitors, while the most sensible prediction would probably be a draw, but I'm throwing caution to the wind.
They have not given me any real reason to back them recently, but I just have a gut instinct Chelsea will emerge victorious because they are at home and they are overdue a victory.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I am at this game and it will be intriguing to see what we get from Liverpool.
I am really pleased for Reds boss Arne Slot to get such a important victory at Inter Milan on Tuesday after all the stuff with Mohamed Salah this week.
Slot shouldn't need to put up with that nonsense. I know Salah has been a icon for Liverpool but at its core Slot just wants to win games and there is nothing personal in his team selection.
Liverpool changed their tactical setup against Inter and went with a midfield diamond and two up top.
All the talk is going to be talking about whether Salah is included for this game, but the only way he is going to be brought back into the fold is if he makes amends.
Slot's focus will be on winning this game, but it is a difficult fixture.
You could argue it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are quite open too.
The Merseysiders need to get back to stringing wins together, but I am not sure how much their energy spent at the San Siro will have affected their stamina.
I have whacked a couple of Brighton players in my FPL team, so they will probably lose now - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the opportunity to rest while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to concede a late equaliser late on.
Apart from their superb performance against Everton a couple of weeks ago, Newcastle's away form hasn't been great, particularly straight after they've played in the Champions League.
I am expecting that trend to continue on Sunday, and their fatigue is likely to be a factor in how this game goes because of their rivals' intensity.
Their match against Arsenal demonstrated how relentless Regis le Bris's side are. They overpowered the Gunners, and it was amazing to watch.
Commentators talks about how Granit Xhaka has been phenomenal for the Black Cats, and he has been superb, but Noah Sadiki, who plays in midfield with him, has also been one of the signings of the season and warrants praise too.
All signs point to this being the best game|most exciting fixture